1. Choose from the list the most likely pathogen that could cause the symptoms or signs described. Each option may be used once, more than once or not at all.

Possible Answers

For each of the questions below, select the answer which is most appropriate. Each option can be used once, more than once or not at all.

a.) A growth scan is performed at 32 weeks. This identifies a small baby with evidence of intracranial and hepatic calcification. The patient reports no history of symptomatic illness to date.

Choose from one of the following answersA CytomegalovirusB Group B streptococcusC Hepatitis BD Herpes simplexE Herpes zosterF HIVG ListeriosisH MalariaI ParvovirusJ RubellaK SyphilisL Toxoplasmosis

b.) A woman develops a mild febrile illness with a macular rash at 9 weeks of pregnancy. After serology is performed, she is offered, and accepts, a termination of pregnancy.

Choose from one of the following answersA CytomegalovirusB Group B streptococcusC Hepatitis BD Herpes simplexE Herpes zosterF HIVG ListeriosisH MalariaI ParvovirusJ RubellaK SyphilisL Toxoplasmosis

c.) A woman at 27 weeks pregnant complains of reduced fetal movements and on ultrasound the fetus is hydropic. Her child had erythema of the cheeks recently.

Choose from one of the following answersA CytomegalovirusB Group B streptococcusC Hepatitis BD Herpes simplexE Herpes zosterF HIVG ListeriosisH MalariaI ParvovirusJ RubellaK SyphilisL Toxoplasmosis

d.) A late booker from sub-Saharan Africa presents with severe anaemia and a baby below the 3rd centile for growth.

Choose from one of the following answersA CytomegalovirusB Group B streptococcusC Hepatitis BD Herpes simplexE Herpes zosterF HIVG ListeriosisH MalariaI ParvovirusJ RubellaK SyphilisL Toxoplasmosis

e.) A French woman presents with a non-specific, febrile illness. On ultrasound, her fetus has cerebral ventriculomegaly.

Choose from one of the following answersA CytomegalovirusB Group B streptococcusC Hepatitis BD Herpes simplexE Herpes zosterF HIVG ListeriosisH MalariaI ParvovirusJ RubellaK SyphilisL Toxoplasmosis

f.) A neonate, born at 35 weeks after prolonged premature rupture of membranes (PROM), is affected by sepsis.

Choose from one of the following answersA CytomegalovirusB Group B streptococcusC Hepatitis BD Herpes simplexE Herpes zosterF HIVG ListeriosisH MalariaI ParvovirusJ RubellaK SyphilisL Toxoplasmosis

g.) An HIV-positive pregnant woman presents with viral pneumonia after spending time with her friend who has a vesicular rash in a dermatomal distribution.

Choose from one of the following answersA CytomegalovirusB Group B streptococcusC Hepatitis BD Herpes simplexE Herpes zosterF HIVG ListeriosisH MalariaI ParvovirusJ RubellaK SyphilisL Toxoplasmosis